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Discuss the condition encompassing clinical experiences and critique the post. Citations: At least one high-level scholarly reference in APA from within the last 5 years
A 22-year-old presents with vaginal discharge, characteristic of green, frothy, and odorous upon exam. The diagnosis is Trichomonas Vaginalis.
Discuss the pathogen and its proliferation.
Trichomonas vaginalis, according to Schumann and Plasner (2022), is a protozoan that causes trichomoniasis which is one of the most common non-viral sexually transmitted infections (STIs) in our country. This disease is sexually transmitted and can be spread by direct sexual contact. Risk factors include a history of STI, new sex partner or multiple partners, contact with an infected partner, abusing IV drugs, and not using a condom during sexual intercourse.
Discuss the male partner treatment. How does metronidazole target the urethral canal?
According to Schumann and Plasner (2022), the drug of choice for trichomoniasis is metronidazole. Treatment for the male partner is metronidazole 2g orally with a single dose, according to CDC (2022). Metronidazole gel is not recommendable because it does not reach the therapeutic levels of the urethra and perivaginal glands. Oral metronidazole treatment is more effective than gel treatment. The mechanism of action of this drug, according to Weir and Lee (2022), is that it diffuses into the organism, and stops protein synthesis by interacting with DNA which causes loss of helical DNA structure and strand breakage. This, therefore, causes cell death in susceptible organisms that can lead to trichomoniasis.
Co-infections are common with STIs. What is the pathogenesis of Chlamydia infection?
Chlamydia infection, according to Mohseni et al. (2022), is a sexually transmitted disease that is caused by the organism or bacteria Chlamydia Trachomatis which is also responsible for the majority of other sexually transmitted infections. C. Trachomatis can also lead to urogenital infections such as cervicitis, pelvic inflammatory disease, urethritis, epididymitis, prostatitis, and lymphogranuloma venereum.
References
Centers for Disease Control and Prevention. (2021, July 22). Trichomoniasis – STI treatment guidelines. Centers for Disease Control and Prevention. Retrieved May 31, 2022, from https://www.cdc.gov/std/treatment-guidelines/trichomoniasis.htm
Mohseni, M., Sung, S., & Takov, V. (2022, April 30). NCBI Bookshelf. Chlamydia. Retrieved June 1, 2022, from https://www.ncbi.nlm.nih.gov/books/NBK537286/
Schumann, J. A., & Plasner, S. (2021, December 13). Trichomoniasis – StatPearls – NCBI Bookshelf. Trichomoniasis. Retrieved May 31, 2022, from https://www.ncbi.nlm.nih.gov/books/NBK534826/
Weir, C. B., & Lee, J. K. (2022, April 20). Metronidazole – StatPearls – NCBI Bookshelf. Metronidazole. Retrieved June 1, 2022, from https://www.ncbi.nlm.nih.gov/books/NBK539728/
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